Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124183 | 0.81 | HDAC1 (0.63) | HDAC3HDAC1HDAC2NCOR2LOXL2 | |
| SCHEMBL24124189 | 0.81 | HDAC8 (0.54) | HDAC3HDAC1HDAC2NCOR2KCNK3 | |
| SCHEMBL24124923 | 0.81 | KMT2A (0.51) | KCNK3KMT2AMEN1NR1H4HPSE | |
| SCHEMBL24124185 | 0.78 | HDAC1 (0.53) | HDAC3HDAC1HDAC2NCOR2KCNK3 | |
| SCHEMBL24124174 | 0.77 | KCNK3 (0.45) | HDAC3HDAC1HDAC2NCOR2KCNK3 | |
| SCHEMBL24124180 | 0.76 | NR1H4 (0.68) | KMT2AMEN1NR1H4POLB | |
| SCHEMBL25920614 | 0.76 | MAPT (0.62) | KMT2AMEN1POLB | |
| SCHEMBL24124886 | 0.75 | LOXL2 (0.44) | HDAC3HDAC1HDAC2NCOR2LOXL2 | |
| SCHEMBL24124182 | 0.75 | KCNK3 (0.40) | KCNK3KMT2AMEN1NR1H4POLB | |
| SCHEMBL25920821 | 0.75 | TRPV1 (0.47) | HDAC3HDAC1HDAC2NCOR2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |