Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412447 | 1.00 | GSK3B (0.32) | GSK3BMAPK14AAK1ROCK2CYP3A4 | |
| SCHEMBL2408955 | 0.92 | WNT3A (0.33) | GSK3BMAPK14AAK1 | |
| SCHEMBL2408961 | 0.92 | WNT3A (0.33) | GSK3BMAPK14AAK1 | |
| SCHEMBL2410451 | 0.89 | ABCB1 (0.31) | — | |
| SCHEMBL2410439 | 0.89 | ABCB1 (0.31) | — | |
| SCHEMBL2408347 | 0.87 | DYRK1A (0.35) | AAK1ROCK2 | |
| SCHEMBL2408349 | 0.87 | DYRK1A (0.35) | AAK1ROCK2 | |
| SCHEMBL316435 | 0.87 | ROCK2 (0.32) | GSK3BAAK1ROCK2 | |
| SCHEMBL316436 | 0.87 | ROCK2 (0.32) | GSK3BAAK1ROCK2 | |
| SCHEMBL2415176 | 0.87 | F2R (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013010-B2 | 5-thioxylopyranose compounds | LABORATOIRES FOURNIER S.A. (FR) | 2011-09-06 | — | — | US | disclosed |
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | LABORATOIRES FOURNIER S.A (FR) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | TPMT, PNPO, CYP3A5 | GSK3B 3081/4885MAPK14 3563/4885AAK1 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.