Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192718 | 0.81 | ALDH1A1 (0.77) | ALDH1A1MAPTPOLBTRPV1GAA | |
| SCHEMBL24124787 | 0.80 | NPC1 (0.51) | ALDH1A1MAPTPOLBTRPV1KMT2A | |
| SCHEMBL24124997 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBTRPV1GAA | |
| SCHEMBL531752 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBTRPV1GAA | |
| SCHEMBL24124652 | 0.79 | PTGER3 (0.49) | ALDH1A1MAPTPOLBGAAKMT2A | |
| SCHEMBL24125117 | 0.79 | PTGER3 (0.49) | ALDH1A1MAPTPOLBGAAKMT2A | |
| SCHEMBL14073692 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MAPTPOLBTRPV1GAA | |
| SCHEMBL24124197 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTPOLBTRPV1GAA | |
| SCHEMBL14073031 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTPOLBTRPV1GAA | |
| SCHEMBL24125184 | 0.74 | HDAC1 (0.56) | ALDH1A1MAPTPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |