Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24125184 | 0.82 | HDAC1 (0.56) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL25927886 | 0.81 | MAPT (0.58) | MAPTALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL24124217 | 0.80 | HDAC1 (0.57) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL24124654 | 0.80 | ALDH1A1 (0.57) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL24125233 | 0.80 | HTT (0.60) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL24124676 | 0.79 | MAPT (0.55) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL24125017 | 0.79 | MAPT (0.55) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL24124910 | 0.78 | KDM4E (0.44) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24125006 | 0.77 | ALDH1A1 (0.59) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24124258 | 0.76 | MAPT (0.43) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |