Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124283 | 0.89 | RAB9A (0.63) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24124808 | 0.86 | RAB9A (0.42) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24124315 | 0.82 | GPR27 (0.53) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL24125091 | 0.81 | RAB9A (0.47) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24125038 | 0.81 | RAB9A (0.60) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24124711 | 0.80 | HDAC1 (0.57) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24124230 | 0.80 | HDAC1 (0.57) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24125168 | 0.80 | RAB9A (0.62) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24125063 | 0.80 | HDAC1 (0.57) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24125188 | 0.80 | HDAC1 (0.54) | RAB9ANPC1MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |