Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2412475

CC(N)(Cc1cccc2ccccc12)Cc1cccc2ccccc12.N

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C9 P11712 1/20 0.47
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
ADRA2A P08913 1/20 0.43
ACHE P22303 1/20 0.43
SLC6A2 P23975 1/20 0.43
HTR2A P28223 1/20 0.43
SLC6A4 P31645 1/20 0.43
KCNH2 Q12809 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
CA2 P00918 1/20 0.42
ACP3 P15309 1/20 0.42
SSTR4 P31391 1/20 0.42
CASR P41180 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8321986 0.90 SLC6A2 (0.48) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL30119619 0.89 CYP1A2 (0.46) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL7037475 0.86 CYP1A2 (0.50) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
Hydrochloric Acid SCHEMBL7217846 0.85 CYP1A2 (0.48) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL11586023 0.82 CYP2D6 (0.53) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL31675157 0.82 CYP2D6 (0.53) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL4814074 0.80 CYP2D6 (0.52) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL7907369 0.78 CYP2C19 (0.50) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL808870 0.78 TDP1 (0.53) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2
SCHEMBL17488720 0.78 CYP2D6 (0.50) CYP1A2CYP2C19CYP2D6CYP2C9NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011116530-A1 STRECKER REAGENTS, THEIR DERIVATIVES, METHODS FOR FORMING THE SAME AND IMPROVED STRECKER REACTION NOWA PHARMACEUTICALS CO., LTD (CN) 2011-09-29 WO disclosed