Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CPT2 | P23786 | 1/20 | 0.47 |
| ▸ | CPT1A | P50416 | 1/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24125006 | 0.88 | ALDH1A1 (0.59) | MAPTSMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL24124258 | 0.85 | MAPT (0.43) | MAPTSMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL24124885 | 0.84 | ALDH1A1 (0.52) | MAPTSMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL24124195 | 0.84 | MAPT (0.44) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL25922279 | 0.84 | CTDSP1 (0.58) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL24124676 | 0.83 | MAPT (0.55) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL24124910 | 0.81 | KDM4E (0.44) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL24125225 | 0.80 | ALDH1A1 (0.51) | MAPTSMN1; SMN2ALDH1A1NPSR1TP53 | |
| SCHEMBL31411638 | 0.77 | MAPT (0.58) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL21972974 | 0.76 | MAPT (0.78) | MAPTLMNASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |