Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124885 | 0.88 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1NPSR1USP2TSHR | |
| SCHEMBL24125006 | 0.86 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1NPSR1USP2TSHR | |
| SCHEMBL25927899 | 0.84 | CTDSP1 (0.55) | ALDH1A1L3MBTL1USP2TSHRMAPT | |
| SCHEMBL24124676 | 0.83 | MAPT (0.55) | ALDH1A1L3MBTL1NPSR1USP2MAPT | |
| SCHEMBL24124910 | 0.82 | KDM4E (0.44) | ALDH1A1L3MBTL1NPSR1USP2TSHR | |
| SCHEMBL24124782 | 0.80 | MAPT (0.55) | ALDH1A1NPSR1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL24124258 | 0.78 | MAPT (0.43) | ALDH1A1L3MBTL1NPSR1USP2TSHR | |
| SCHEMBL24124195 | 0.77 | MAPT (0.44) | ALDH1A1L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL24125231 | 0.77 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1NPSR1USP2TSHR | |
| SCHEMBL25926503 | 0.74 | RAB9A (0.54) | ALDH1A1NPSR1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |