Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124853 | 0.77 | LMNA (0.70) | LMNASMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL5340775 | 0.71 | ALDH1A1 (0.56) | LMNASMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL24124962 | 0.68 | MAPT (0.47) | LMNASMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL8711321 | 0.66 | BCHE (0.41) | LMNASMN1; SMN2ALDH1A1ALDH1A3MEN1 | |
| SCHEMBL9920472 | 0.65 | LMNA (0.58) | LMNASMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL6177638 | 0.64 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1ALDH1A3MEN1KMT2A | |
| SCHEMBL622422 | 0.64 | HTT (0.56) | LMNAPOLBALDH1A1KMT2AHTT | |
| SCHEMBL17821428 | 0.62 | KMT2A (0.46) | SMN1; SMN2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL14518825 | 0.62 | MAPT (0.56) | LMNASMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL10022341 | 0.62 | ALDH1A1 (0.52) | LMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |