Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124783 | 0.87 | ALDH1A1 (0.47) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24124884 | 0.78 | MAPT (0.64) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24124676 | 0.77 | MAPT (0.55) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24124188 | 0.77 | MAPT (0.62) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL25920636 | 0.76 | MAPT (0.60) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24124885 | 0.74 | ALDH1A1 (0.52) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24124186 | 0.74 | MAPT (0.57) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24124264 | 0.74 | MAPT (0.57) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24124898 | 0.74 | MAPT (0.57) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24125225 | 0.73 | ALDH1A1 (0.51) | MAPTKMT2AMEN1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |