Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4427593 | 0.95 | PTGDR2 (0.31) | PTGDR2PLCG1 | |
| SCHEMBL2414626 | 0.92 | PLCG1 (0.32) | PLCG1P2RX7PIK3C3 | |
| SCHEMBL2409999 | 0.91 | PTPN1 (0.33) | PTGDR2PLCG1LMNA | |
| SCHEMBL2411190 | 0.90 | PLCG1 (0.30) | PLCG1 | |
| SCHEMBL2417456 | 0.90 | PLCG1 (0.30) | PLCG1 | |
| SCHEMBL2409826 | 0.90 | PTGDR2 (0.38) | PTGDR2PLCG1P2RX7CTSLMET | |
| SCHEMBL2406674 | 0.90 | PTGDR2 (0.33) | PTGDR2PLCG1P2RX7 | |
| SCHEMBL2410587 | 0.89 | PTGDR2 (0.33) | PTGDR2PLCG1P2RX7 | |
| SCHEMBL2410416 | 0.88 | PTGDR2 (0.33) | PTGDR2PLCG1P2RX7CTSL | |
| SCHEMBL2410363 | 0.88 | PKM (0.35) | PLCG1LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |