Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414626 | 0.93 | PLCG1 (0.32) | PLCG1 | |
| SCHEMBL2406674 | 0.91 | PTGDR2 (0.33) | PTGDR2PLCG1 | |
| SCHEMBL2409826 | 0.91 | PTGDR2 (0.38) | ITGB1ITGA4PTGDR2PLCG1 | |
| SCHEMBL2412640 | 0.91 | PTGDR2 (0.33) | LMNAPTGDR2PLCG1 | |
| SCHEMBL2415541 | 0.87 | GRM4 (0.34) | LMNAPTGDR2PLCG1 | |
| Hydrochloric Acid SCHEMBL4427593 | 0.87 | PTGDR2 (0.31) | PTGDR2PLCG1 | |
| SCHEMBL2410587 | 0.86 | PTGDR2 (0.33) | PTGDR2PLCG1 | |
| SCHEMBL2410363 | 0.86 | PKM (0.35) | ITGB1ITGA4LMNAPLCG1 | |
| SCHEMBL2416580 | 0.86 | PLCG1 (0.31) | PLCG1 | |
| SCHEMBL2417456 | 0.85 | PLCG1 (0.30) | PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |