Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 3/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4427592 | 0.95 | HTR2C (0.34) | HTR2CSLC6A4CTSLCTSBCTSS | |
| SCHEMBL2410003 | 0.90 | HTR2C (0.34) | HTR2CSLC6A4CTSLCTSBCTSS | |
| SCHEMBL2414628 | 0.90 | TACR1 (0.35) | HTR2CSLC6A4CTSLCTSBCTSS | |
| SCHEMBL2406675 | 0.90 | HTR2C (0.34) | HTR2CSLC6A4CTSLCTSBCTSS | |
| SCHEMBL2417461 | 0.90 | GLS (0.32) | HTR2CSLC6A4GLSPLCG1 | |
| SCHEMBL2411191 | 0.90 | HTR2C (0.31) | HTR2CSLC6A4PLCG1 | |
| SCHEMBL2409829 | 0.90 | HTR2C (0.35) | HTR2CSLC6A4CTSLCTSBCTSS | |
| SCHEMBL2408479 | 0.89 | HTR6 (0.36) | HTR6TNFKMT2APTGDR2LMNA | |
| SCHEMBL2410418 | 0.88 | RET (0.33) | HTR2CSLC6A4PLCG1RORCPTGDR2 | |
| SCHEMBL2415723 | 0.88 | HTR2C (0.39) | HTR2CSLC6A4GLSF2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |