Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790986 | 0.86 | ALOX15 (0.47) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL18432461 | 0.81 | GABRP (0.48) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL13199300 | 0.79 | KDM4E (0.42) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL16527178 | 0.79 | CYP3A4 (0.45) | HPGDCYP3A4GAAALDH1A1NPSR1 | |
| SCHEMBL11773187 | 0.77 | CSNK2A1 (0.53) | KDM4ECYP3A4GAAALDH1A1NOTUM | |
| SCHEMBL30742613 | 0.76 | ALOX15 (0.46) | KDM4EHPGDHSD17B10GAANPSR1 | |
| SCHEMBL28183452 | 0.76 | KDM4E (0.50) | KDM4EHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL5691127 | 0.75 | CYP3A4 (0.42) | KDM4EHPGDHSD17B10CYP3A4GAA | |
| SCHEMBL30442476 | 0.75 | KDM4E (0.54) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL235710 | 0.75 | KDM4E (0.54) | KDM4EHPGDHSD17B10GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257669-A1 | SYNTHESIS OF SUBSTITUTED ARYLMETHYLUREAS, ANALOGUES, AND CRYSTALLINE FORMS THEREOF AND METHODS OF USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-12-23 | — | — | WO | disclosed |