Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924035 | 0.82 | CYP2D6 (0.52) | CYP2D6MC4RCHRM2CHRM1ALDH1A1 | |
| SCHEMBL18403967 | 0.80 | ALDH1A1 (0.53) | CYP2D6MC4RCHRM2CHRM1ALDH1A1 | |
| SCHEMBL14924473 | 0.80 | ALDH1A1 (0.53) | CYP2D6MC4RCHRM2CHRM1ALDH1A1 | |
| SCHEMBL18403964 | 0.79 | GAA (0.54) | CYP2D6MC4RCHRM2CHRM1ALDH1A1 | |
| SCHEMBL10112423 | 0.79 | CYP2D6 (0.50) | CYP2D6MC4RCHRM2CHRM1L3MBTL1 | |
| SCHEMBL19251271 | 0.79 | CYP2D6 (0.48) | CYP2D6MC4RTSHRCHRM2CHRM1 | |
| SCHEMBL20012737 | 0.78 | CYP2D6 (0.74) | CYP2D6MC4RCHRM2CHRM1ALDH1A1 | |
| SCHEMBL14600336 | 0.78 | CYP2D6 (0.74) | CYP2D6MC4RCHRM2CHRM1ALDH1A1 | |
| SCHEMBL13380751 | 0.74 | ATM (0.51) | CYP2D6MC4RCHRM2CHRM1ALDH1A1 | |
| SCHEMBL24322973 | 0.70 | CYP2D6 (0.53) | CYP2D6ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021255518-A1 | COMPOSITIONS AND METHODS FOR TREATING ACUTE MYELOID LEUKEMIA | RIKEN (JP) | 2021-12-23 | — | — | WO | disclosed |