Malonic Acid

Malonic Acid

SCHEMBL2412964

COC.O=C(O)CC(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.69
SRR Q9GZT4 1/20 0.69
TSHR P16473 7/20 0.46
ALDH1A1 P00352 2/20 0.44
FFAR3 O14843 2/20 0.44
EGLN1 Q9GZT9 2/20 0.43
HSD17B10 Q99714 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
LMNA P02545 2/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
HCAR2 Q8TDS4 2/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL2509322 1.00 LDHA (0.69) LDHASRRTSHRALDH1A1FFAR3
Malonic Acid SCHEMBL27706336 0.93 LDHA (0.60) LDHASRRTSHRALDH1A1FFAR3
Malonic Acid SCHEMBL10817903 0.86 LDHA (0.60) LDHASRRTSHRALDH1A1FFAR3
Malonic Acid SCHEMBL3608474 0.84
Malonic Acid SCHEMBL782125 0.84
Malonic Acid SCHEMBL1332554 0.83
Malonic Acid SCHEMBL336 0.83
Malonic Acid SCHEMBL1332587 0.83
Malonic Acid SCHEMBL1332405 0.83
Malonic Acid SCHEMBL3358611 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115636951-B Modified aqueous single-component epoxy emulsion, self-drying epoxy primer and preparation method thereof 安徽衡光新材料科技有限公司 2024-07-12 CN claimed
CN-118028031-A Industrial modified methanol fuel and preparation method thereof 闳然(重庆)新能源技术开发有限公司 2024-05-14 CN claimed
CN-116535967-A Rubbing UV finishing paint and preparation method and application thereof 湖南松井新材料股份有限公司 2023-08-04 CN claimed
CN-110760226-A Environment-friendly building interior wall coating and preparation method thereof 浙江迈实科技有限公司 2020-02-07 CN claimed
CN-115636951-B Modified aqueous single-component epoxy emulsion, self-drying epoxy primer and preparation method thereof 安徽衡光新材料科技有限公司 2024-07-12 CN disclosed
CN-118028031-A Industrial modified methanol fuel and preparation method thereof 闳然(重庆)新能源技术开发有限公司 2024-05-14 CN disclosed
CN-109180425-B Refining process and system for acetic ester recovery liquid containing cyclopentanone and propylene glycol methyl ether 江阴市大洋固废处置利用有限公司 2024-03-19 CN disclosed
CN-116535967-A Rubbing UV finishing paint and preparation method and application thereof 湖南松井新材料股份有限公司 2023-08-04 CN disclosed
CN-107219725-B Photosensitive resin composition, color filter and image display device manufactured using the same 东友精细化工有限公司 2022-07-05 CN disclosed
CN-113372801-A PU (polyurethane) antibacterial paint as well as preparation method and application thereof 湖南松井新材料股份有限公司 2021-09-10 CN disclosed
CN-113337202-A UV (ultraviolet) finish paint as well as preparation method and application thereof 湖南松井新材料股份有限公司 2021-09-03 CN disclosed
CN-113337201-A Primer and preparation method and application thereof 湖南松井新材料股份有限公司 2021-09-03 CN disclosed
CN-101490183-A Dry erase ink for non-porous surfaces EDDING AG (DE) 2009-07-22 CN disclosed
WO-2009008980-A2 TETRAHYDROPYRANOCHROMENE GAMMA SECRETASE INHIBITORS SCHERING CORPORATION (US) 2009-01-15 WO disclosed
US-20080127857-A1 A polylactone-poly(trimethylenecarbonate) copolymer with one endcap and sulfate or phosphate residue on the other end; millbases, paints or inks, including ink jet inks; improved fluid flow, photostability and colorfastness THE LUBRIZOL CORPORATION (US) 2008-06-05 US disclosed
US-7361692-B2 Dispersants THE LUBRIZOL CORPORATION (US) 2008-04-22 US disclosed
EP-1383595-B1 DISPERSANTS LUBRIZOL CORP (US) 2005-07-06 EP disclosed
US-20040112250-A1 Dispersants LUBRIZOL CORPORATION, THE 2004-06-17 US disclosed
EP-1383595-A2 DISPERSANTS Avecia Limited (GB) 2004-01-28 EP disclosed
WO-2002085507-A2 DISPERSANTS AVECIA LIMITED (GB) 2002-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080127857-A1 A polylactone-poly(trimethylenecarbonate) copolymer with one endcap and sulfate or phosphate residue on the other end; millbases, paints or inks, including ink jet inks; improved fluid flow, photostability and colorfastness INPP5A, PHPT1, IPMK LDHA 1531/4885SRR 2907/4885TSHR 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.