Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1602296 | 0.82 | S1PR1 (0.85) | S1PR1S1PR3KCNH2 | |
| SCHEMBL12319320 | 0.81 | S1PR1 (0.63) | S1PR1S1PR3KCNH2MAOBMAOA | |
| SCHEMBL1601740 | 0.79 | S1PR1 (0.68) | S1PR1S1PR3KCNH2MAOBMAOA | |
| SCHEMBL1601626 | 0.78 | S1PR1 (0.61) | S1PR1S1PR3KCNH2MAOB | |
| SCHEMBL12318147 | 0.77 | S1PR1 (0.63) | S1PR1S1PR3KCNH2MAOBMAOA | |
| SCHEMBL2414430 | 0.74 | S1PR1 (0.67) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1603237 | 0.74 | S1PR1 (1.00) | S1PR1S1PR3KCNH2 | |
| SCHEMBL9543098 | 0.73 | MAPT (0.50) | S1PR1 | |
| SCHEMBL2420094 | 0.73 | S1PR1 (0.54) | S1PR1S1PR3KCNH2MAOBMAOA | |
| SCHEMBL2415217 | 0.72 | S1PR1 (0.53) | S1PR1S1PR3KCNH2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364976-A1 | S1P receptor modulating compounds and use thereof | EPIX Pharmaceuticals, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |