Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 16/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.44 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445113 | 0.88 | KCNJ1 (0.48) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL20168335 | 0.88 | KCNJ1 (0.48) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL21243688 | 0.85 | KCNJ1 (0.47) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL28362242 | 0.84 | KCNJ1 (0.43) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL20176738 | 0.82 | KCNJ1 (0.41) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL23586685 | 0.80 | KCNJ1 (0.57) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL24135356 | 0.77 | KCNJ1 (0.42) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL20168616 | 0.77 | KCNJ1 (0.42) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL30445170 | 0.77 | KCNJ1 (0.42) | KCNJ1KCNH2ABCB11POU2F2POU2F1 | |
| SCHEMBL30444639 | 0.77 | KCNJ1 (0.52) | KCNJ1KCNH2ABCB11POU2F2POU2F1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929194-A1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | Bristol-Myers Squibb Company (US) | 2021-12-29 | — | — | EP | disclosed |