SCHEMBL24136148

SCHEMBL24136148

C=Cc1ccccc1-c1cc(CO[Si](CC)(CC)CC)ccc1C=C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.31
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19089877 0.72 ALDH1A1 (0.39) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL24136147 0.71 ALDH1A1 (0.41) ALDH1A1MAPT
SCHEMBL18297917 0.68 TSHR (0.48) ALDH1A1LMNAMAPTMAPK1L3MBTL1
SCHEMBL5888602 0.67 ALDH1A1 (0.36) ALDH1A1LMNAMAPTMAPK1SMN1; SMN2
SCHEMBL132630 0.67 ALDH1A1 (0.55) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL19243812 0.66 ALDH1A1 (0.35) ALDH1A1
SCHEMBL1155712 0.66 ESR1 (0.31)
SCHEMBL7107668 0.65 ALDH1A1 (0.52) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL28281823 0.65 ALDH1A1 (0.52) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL4508207 0.64 TP53 (0.41) NPC1ALDH1A1LMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11208534-B2 Dynamic polymers based on silyl ether exchange THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-12-28 US disclosed