Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728679 | 0.80 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL4626896 | 0.76 | ALDH1A1 (0.43) | ALDH1A1GABRA1GABRB2 | |
| SCHEMBL132630 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EMEN1PPARG | |
| SCHEMBL28281823 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EMEN1PPARG | |
| SCHEMBL7107668 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EMEN1PPARG | |
| SCHEMBL30595108 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL809726 | 0.73 | ALDH1A1 (0.45) | ALDH1A1TTRKDM4EMEN1KMT2A | |
| SCHEMBL1264548 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL24136148 | 0.72 | PSMB5 (0.31) | ALDH1A1MAPTNPC1LMNAMAPK1 | |
| SCHEMBL15524544 | 0.72 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179517-A9 | Monoliths with Attached Recognition Compounds, Arrays Thereof and Uses Thereof | DICE MOLECULES SV, LLC | 2018-06-28 | — | — | US | disclosed |
| US-20170191056-A1 | Monoliths with Attached Recognition Compounds, Arrays Thereof and Uses Thereof | DICE MOLECULES SV LLC (US) | 2017-07-06 | — | — | US | disclosed |