Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136445 | 0.86 | GRIN2B (0.50) | GRIN2BGRIN1 | |
| SCHEMBL24270944 | 0.77 | — | — | |
| SCHEMBL22239239 | 0.76 | GRIN2B (0.49) | GRIN2BGRIN1 | |
| SCHEMBL22239252 | 0.74 | GRIN2B (0.40) | GRIN2BGRIN1 | |
| SCHEMBL26020473 | 0.74 | GRIN2B (0.47) | GRIN2BGRIN1 | |
| SCHEMBL22239269 | 0.73 | KMT2A (0.46) | GRIN2B | |
| SCHEMBL22239272 | 0.73 | KDM4E (0.35) | GRIN2BGRIN1 | |
| SCHEMBL24270860 | 0.70 | — | — | |
| SCHEMBL24270830 | 0.68 | GRIN2B (0.48) | GRIN2BGRIN1 | |
| SCHEMBL24271025 | 0.67 | GRIN2B (0.40) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683207-B1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | CADENT THERAPEUTICS INC (US) | 2021-12-29 | — | — | EP | disclosed |