Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329220 | 0.73 | PDE3B (0.50) | CHEK1MAOAKDM4EMEN1ALDH1A1 | |
| SCHEMBL21593366 | 0.72 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL3951034 | 0.70 | ROCK1 (0.46) | MAOAKDM4EMCL1ALDH1A1HPGD | |
| SCHEMBL1204984 | 0.70 | ROCK1 (0.55) | MAPTKDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL18257252 | 0.69 | PDE3B (0.40) | MAPTKDM4EMCL1MEN1ALDH1A1 | |
| SCHEMBL4296227 | 0.69 | CHEK1 (0.54) | CHEK1KDM4ECA12CA1CA7 | |
| SCHEMBL30466409 | 0.68 | PARP1 (0.43) | CHEK1KDM4EALDH1A1CYP2C9HPGD | |
| SCHEMBL24136691 | 0.68 | PARP1 (0.43) | CHEK1KDM4EALDH1A1CYP2C9HPGD | |
| SCHEMBL9315325 | 0.68 | TUBB4A (0.41) | MAPTKDM4ECA12CA1CA7 | |
| SCHEMBL29039486 | 0.68 | ALDH1A1 (0.58) | MAPTCHEK1KDM4EALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194108-B | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-116194108-A | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2023-05-30 | — | — | CN | disclosed |
| US-11535629-B2 | Dioxoloisoquinolinone derivatives and use thereof | HANMI PHARMACEUTICAL CO., LTD. (KR) | 2022-12-27 | — | — | US | disclosed |
| US-20220135582-A1 | NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME | HANMI PHARMACEUTICAL CO., LTD. (KR) | 2022-05-05 | — | — | US | disclosed |
| EP-3929199-A1 | NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME | Hanmi Pharmaceutical Co., Ltd. (KR) | 2021-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535629-B2 | Dioxoloisoquinolinone derivatives and use thereof | EZH2, EZH1, EED | MAPT 1430/4885CHEK1 3195/4885MAOA 3143/4885 |
| US-20220135582-A1 | NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME | EZH2, EZH1, BMI1 | MAPT 4574/4885CHEK1 3978/4885MAOA 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.