Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.34 |
| ▸ | HEXB | P07686 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | SDHB | P21912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506654 | 0.81 | TRPV4 (0.31) | TRPV4P2RX7LMNA | |
| SCHEMBL21419162 | 0.78 | HEXA (0.35) | HEXAHEXBMTORPIK3CAKDM4E | |
| SCHEMBL13064436 | 0.77 | TRPV3 (0.38) | HEXAHEXBKDM4ECXCR4LMNA | |
| SCHEMBL16068142 | 0.77 | HEXA (0.41) | HEXAHEXBMTORPIK3CAKDM4E | |
| SCHEMBL25271011 | 0.77 | HEXA (0.34) | HEXAHEXBMTORPIK3CAKDM4E | |
| SCHEMBL30408730 | 0.77 | HEXA (0.34) | HEXAHEXBMTORPIK3CAKDM4E | |
| SCHEMBL4492952 | 0.74 | TKT (0.36) | HEXAHEXBMTORKDM4ECXCR4 | |
| SCHEMBL22868494 | 0.74 | CYP3A4 (0.34) | HEXAHEXBKDM4ECXCR4PDE4B | |
| SCHEMBL4760947 | 0.74 | CNR1 (0.34) | HEXAHEXBKDM4ECXCR4PDE4B | |
| SCHEMBL4488040 | 0.74 | CNR1 (0.36) | HEXAHEXBKDM4ECXCR4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928779-A1 | PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. | Chugai Seiyaku Kabushiki Kaisha (JP) | 2021-12-29 | — | — | EP | disclosed |