Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.62 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14652011 | 0.79 | GRIA1 (0.75) | GRIA1GRIA4NPY5RHTR1ATP53 | |
| SCHEMBL7109326 | 0.78 | GRIA1 (1.00) | GRIA1GRIA4NPY5RCA1CA2 | |
| SCHEMBL7039391 | 0.78 | GRIA1 (1.00) | GRIA1GRIA4NPY5RCA1CA2 | |
| SCHEMBL7042049 | 0.78 | GRIA1 (1.00) | GRIA1GRIA4NPY5RCA1CA2 | |
| SCHEMBL12449173 | 0.77 | GRIA1 (0.71) | GRIA1GRIA4NPY5RHTR1ACA1 | |
| SCHEMBL2058109 | 0.75 | THRB (0.44) | THRBTP53ACACBACACA | |
| SCHEMBL2057715 | 0.73 | THRB (0.42) | THRBACACBACACA | |
| SCHEMBL2057812 | 0.73 | THRB (0.42) | THRBACACBACACA | |
| SCHEMBL23542459 | 0.72 | GRIA1 (0.71) | GRIA1GRIA4NPY5RCA1CA2 | |
| SCHEMBL14654996 | 0.72 | GRIA1 (0.78) | GRIA1TP53CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263039-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2021-12-30 | — | — | WO | disclosed |