Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | EEF2K | O00418 | 3/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP10 | P09238 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407247 | 0.80 | EEF2K (0.55) | MMP7MMP9MMP13MMP1MMP2 | |
| SCHEMBL2413093 | 0.75 | MMP7 (0.52) | MMP7MMP9MMP13MMP1MMP2 | |
| SCHEMBL2412670 | 0.75 | MMP7 (0.52) | MMP7MMP9MMP13MMP1MMP2 | |
| SCHEMBL2406492 | 0.73 | EEF2K (0.49) | MMP7MMP9MMP13MMP1MMP2 | |
| SCHEMBL2412284 | 0.71 | CYP3A4 (0.53) | MMP7MMP9MMP13MMP1MMP2 | |
| SCHEMBL2407249 | 0.71 | CYP3A4 (0.53) | MMP7MMP9MMP13MMP1MMP2 | |
| SCHEMBL1447588 | 0.71 | KDM4E (0.53) | CYP2C19MAPTHTTTSHRALDH1A1 | |
| SCHEMBL12377249 | 0.70 | CA1 (0.61) | MMP7MMP9MMP13MMP1MMP2 | |
| SCHEMBL14162932 | 0.68 | TRPA1 (0.57) | CA2CA1CYP3A4CYP2C9GAA | |
| SCHEMBL968120 | 0.68 | HDAC3 (0.54) | MMP7MMP9MMP13MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |