SCHEMBL24142256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24142255	0.85	ADRB2 (0.50)	SERPINE1CES2CES1ADRB2ADRB1
	SCHEMBL24142253	0.84	ADRB2 (0.49)	MEN1KMT2AADRB2ADRB1ADRB3
	SCHEMBL24177738	0.83	SERPINE1 (0.41)	SERPINE1TYRL3MBTL1ESR1POLB
	SCHEMBL24142638	0.83	KMT2A (0.35)	SERPINE1MEN1KMT2A
	SCHEMBL12972080	0.83	SERPINE1 (0.43)	SERPINE1MEN1KMT2ACES2CES1
	SCHEMBL24142637	0.81	CES2 (0.42)	SERPINE1CES2CES1TYRADRB2
	SCHEMBL24142667	0.79	TDP1 (0.56)	KMT2AADRB2ADRB1ADRB3ESR1
	SCHEMBL12977549	0.79	SERPINE1 (0.40)	SERPINE1MEN1KMT2ACES2CES1
	SCHEMBL24142186	0.77	MAPT (0.46)	MEN1KMT2AADRB2ADRB1ADRB3
	SCHEMBL24142250	0.77	GSK3B (0.46)	MEN1KMT2ACES2CES1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.