Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 19/20 | 0.65 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24143783 | 0.87 | NR1D1 (0.67) | NR1D1ICMT | |
| SCHEMBL24142979 | 0.87 | NR1D1 (0.67) | NR1D1ICMT | |
| SCHEMBL24144015 | 0.84 | NR1D1 (0.63) | NR1D1ICMT | |
| SCHEMBL24143626 | 0.84 | ICMT (0.56) | NR1D1ICMT | |
| SCHEMBL24144026 | 0.83 | NR1D1 (0.64) | NR1D1ICMT | |
| SCHEMBL24144454 | 0.83 | NR1D1 (0.47) | NR1D1ICMT | |
| SCHEMBL24144064 | 0.82 | NR1D1 (0.54) | NR1D1ICMT | |
| SCHEMBL24144066 | 0.82 | NR1D1 (0.61) | NR1D1ICMT | |
| SCHEMBL24144060 | 0.81 | NR1D1 (0.54) | NR1D1ICMT | |
| SCHEMBL24144021 | 0.81 | NR1D1 (0.52) | NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263278-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-12-30 | — | — | WO | disclosed |