Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21112932 | 0.92 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1GAAHTTAKR1C3 | |
| SCHEMBL24145057 | 0.90 | TP53 (0.43) | SMN1; SMN2ALDH1A1GAAMAPK1KMT2A | |
| SCHEMBL24145051 | 0.89 | MEN1 (0.45) | SMN1; SMN2ALDH1A1HTTAKR1C3KDM4E | |
| SCHEMBL24145052 | 0.89 | TFPI2 (0.42) | SMN1; SMN2HTTAKR1C3L3MBTL1MAPK1 | |
| SCHEMBL24145067 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GAAHTTAKR1C3MAPK1 | |
| SCHEMBL20873248 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL24145178 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1GAAAKR1C3MAPK1 | |
| SCHEMBL20873315 | 0.81 | MEN1 (0.50) | SMN1; SMN2ALDH1A1HTTAKR1C3L3MBTL1 | |
| SCHEMBL20873341 | 0.81 | AKR1C3 (0.44) | SMN1; SMN2ALDH1A1GAAAKR1C3KMT2A | |
| SCHEMBL20873345 | 0.80 | TFPI2 (0.47) | SMN1; SMN2ALDH1A1HTTAKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | SMN1; SMN2 4049/4885ALDH1A1 1514/4885GAA 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.