Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21148305 | 0.84 | AKR1C3 (0.39) | AKR1C3GRM5LMNAMAPK1MEN1 | |
| SCHEMBL21148306 | 0.80 | AKR1C3 (0.46) | AKR1C3GRM5LMNAMEN1KMT2A | |
| SCHEMBL24137717 | 0.77 | AKR1C3 (0.41) | AKR1C3GRM5LMNAMAPK1MEN1 | |
| SCHEMBL21149337 | 0.72 | AKR1C3 (0.51) | AKR1C3GRM5LMNAMAPK1MAPT | |
| SCHEMBL30208133 | 0.64 | MEN1 (0.58) | AKR1C3GRM5LMNAMAPK1MEN1 | |
| SCHEMBL2365793 | 0.64 | MEN1 (0.58) | AKR1C3GRM5LMNAMAPK1MEN1 | |
| SCHEMBL24145194 | 0.64 | AKR1C3 (0.53) | AKR1C3GRM5ALDH1A1GAA | |
| SCHEMBL22581762 | 0.61 | PHGDH (0.45) | AKR1C3GRM5MAPTKDM4E | |
| SCHEMBL30567128 | 0.61 | PHGDH (0.45) | AKR1C3GRM5MAPTKDM4E | |
| SCHEMBL1902475 | 0.61 | MEN1 (0.63) | AKR1C3GRM5LMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | AKR1C3 1463/4885GRM5 1859/4885LMNA 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.