Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | GRM5 | P41594 | 14/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21149337 | 0.81 | AKR1C3 (0.51) | AKR1C3GRM5NOTUMALDH1A1GAA | |
| SCHEMBL23777678 | 0.72 | AKR1C3 (0.66) | AKR1C3GRM5NOTUMALDH1A1NR1H4 | |
| SCHEMBL24137717 | 0.71 | AKR1C3 (0.41) | AKR1C3GRM5 | |
| SCHEMBL21148306 | 0.70 | AKR1C3 (0.46) | AKR1C3GRM5NOTUMNR1H4GAA | |
| SCHEMBL21432539 | 0.70 | AKR1C3 (1.00) | AKR1C3ALDH1A1 | |
| SCHEMBL31758889 | 0.69 | HPGD (0.44) | ALDH1A1 | |
| SCHEMBL1904905 | 0.69 | AKR1C3 (0.61) | AKR1C3GRM5ALDH1A1 | |
| SCHEMBL1903214 | 0.69 | GRM5 (0.64) | AKR1C3GRM5 | |
| SCHEMBL12781995 | 0.68 | TSHR (0.70) | AKR1C3GRM5ALDH1A1GAA | |
| SCHEMBL31759010 | 0.68 | L3MBTL1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | AKR1C3 1463/4885GRM5 1859/4885NOTUM 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.