Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24149020 | 0.89 | DOT1L (0.37) | CSNK2A2CSNK2A1POLRMT | |
| SCHEMBL19504133 | 0.85 | DOT1L (0.32) | POLRMT | |
| SCHEMBL18666884 | 0.85 | DOT1L (0.32) | POLRMT | |
| SCHEMBL24058411 | 0.85 | DOT1L (0.32) | POLRMT | |
| SCHEMBL22355507 | 0.85 | DOT1L (0.32) | POLRMT | |
| SCHEMBL24149875 | 0.83 | DOT1L (0.35) | — | |
| SCHEMBL22355532 | 0.83 | BTN3A1 (0.34) | POLRMT | |
| SCHEMBL24158211 | 0.82 | DOT1L (0.34) | POLRMT | |
| SCHEMBL24148687 | 0.81 | BTN3A1 (0.33) | — | |
| SCHEMBL23047641 | 0.80 | CYP3A4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262826-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2021-12-30 | — | — | WO | disclosed |