Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985367 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7857566 | 0.79 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL926606 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL14808336 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL14357370 | 0.75 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL12859809 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL927482 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL130928 | 0.74 | — | — | |
| SCHEMBL15199621 | 0.74 | — | — | |
| SCHEMBL19321817 | 0.73 | NR3C1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250064-A1 | PREPARATION METHOD FOR FUSED PYRAZOLE-TYPE COMPOUND | WUHAN CREATERNA SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
| US-20230250064-A1 | PREPARATION METHOD FOR FUSED PYRAZOLE-TYPE COMPOUND | WUHAN CREATERNA SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
| WO-2021259163-A1 | PREPARATION METHOD FOR FUSED PYRAZOLE-TYPE COMPOUND | 上海美悦生物科技发展有限公司 | 2021-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250064-A1 | PREPARATION METHOD FOR FUSED PYRAZOLE-TYPE COMPOUND | AZI2, HRH4, HRH2 | ALDH1A1 382/4885CYP2C9 76/4885CYP2C19 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.