Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 12/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414223 | 0.79 | LAP3 (0.34) | — | |
| SCHEMBL14655413 | 0.78 | MEN1 (0.53) | MEN1KMT2ATLR2CA2 | |
| SCHEMBL2417339 | 0.75 | LAP3 (0.31) | — | |
| SCHEMBL2413471 | 0.75 | LAP3 (0.31) | — | |
| SCHEMBL161534 | 0.75 | LAP3 (0.31) | — | |
| SCHEMBL13255060 | 0.72 | MEN1 (0.59) | MEN1KMT2ATLR2CA2 | |
| SCHEMBL2415106 | 0.71 | MEN1 (0.47) | MEN1KMT2ATLR2CA2S1PR1 | |
| SCHEMBL22307909 | 0.69 | MEN1 (0.55) | MEN1KMT2ATLR2CA2 | |
| SCHEMBL9122686 | 0.69 | MEN1 (0.55) | MEN1KMT2ATLR2CA2 | |
| SCHEMBL13360298 | 0.68 | MEN1 (0.54) | MEN1KMT2ATLR2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365506-B2 | Compounds and compositions as TLR2 agonists | NOVARTIS AG (CH) | 2016-06-14 | — | — | US | disclosed |
| WO-2011119759-A1 | COMPOUNDS (CYSTEIN BASED LIPOPEPTIDES) AND COMPOSITIONS AS TLR2 AGONISTS USED FOR TREATING INFECTIONS, INFLAMMATIONS, RESPIRATORY DISEASES ETC. | IRM LLC (BM) | 2011-09-29 | — | — | WO | disclosed |