Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 5/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153273 | 0.97 | TRPA1 (0.36) | TRPA1CASP3CASP7KDM4ELMNA | |
| SCHEMBL24152457 | 0.91 | KDM4E (0.33) | TRPA1KDM4ELMNATAS2R14PTGS2 | |
| SCHEMBL24152488 | 0.88 | SMN1; SMN2 (0.33) | TRPA1CASP3CASP7KDM4ELMNA | |
| SCHEMBL24152507 | 0.85 | KDM4E (0.33) | TRPA1KDM4ELMNATAS2R14PTGS2 | |
| SCHEMBL24153267 | 0.83 | TRPA1 (0.48) | TRPA1CASP3CASP7TAS2R14MAOA | |
| SCHEMBL24153270 | 0.83 | TRPA1 (0.39) | TRPA1CASP3CASP7KDM4ELMNA | |
| SCHEMBL24153265 | 0.81 | TRPA1 (0.37) | TRPA1CASP3CASP7KDM4ELMNA | |
| SCHEMBL24152504 | 0.80 | TAS2R14 (0.41) | TRPA1CASP3KDM4ELMNATAS2R14 | |
| SCHEMBL24152818 | 0.80 | TRPA1 (0.34) | TRPA1CASP3KDM4ELMNATAS2R14 | |
| SCHEMBL24152493 | 0.80 | PTGS1 (0.37) | TRPA1CASP3KDM4ELMNATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |