Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 7/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411684 | 0.80 | SMPD3 (0.48) | MAP4K4PDE10APTPN11 | |
| Hydrochloric Acid SCHEMBL6336102 | 0.79 | SMPD3 (0.47) | MAP4K4PDE10APTPN11 | |
| SCHEMBL2415129 | 0.78 | HRH4 (0.53) | MAP4K4PDE10APRKCQPTPN11 | |
| SCHEMBL15652803 | 0.77 | MAP4K4 (0.48) | MAP4K4PTGER4PDE10A | |
| SCHEMBL15652802 | 0.77 | MAP4K4 (0.48) | MAP4K4PTGER4PDE10A | |
| SCHEMBL31703895 | 0.77 | PDE10A (0.43) | MAP4K4PTGER4PDE10A | |
| SCHEMBL113232 | 0.76 | SMPD3 (0.55) | MAP4K4PTGER4PDE10APTPN11 | |
| SCHEMBL2416331 | 0.73 | MAP4K4 (0.43) | MAP4K4PTGER4PDE10A | |
| SCHEMBL18291297 | 0.73 | PTGER4 (0.46) | MAP4K4PTGER4PDE10A | |
| SCHEMBL2413196 | 0.73 | PDE10A (0.39) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |