Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152357 | 0.91 | TRPA1 (0.54) | TRPA1MAOAMAPK14CASP3CA12 | |
| SCHEMBL24152847 | 0.90 | TRPA1 (0.41) | TRPA1CASP3PTGS1PTGS2LMNA | |
| SCHEMBL24151587 | 0.89 | TRPA1 (0.42) | TRPA1CASP3LMNAPOLBMAPT | |
| SCHEMBL24152462 | 0.87 | TRPA1 (0.41) | TRPA1CASP3LMNAPOLBMAPT | |
| SCHEMBL24152464 | 0.87 | TRPA1 (0.41) | TRPA1CASP3LMNAPOLBMAPT | |
| SCHEMBL24152830 | 0.86 | TRPA1 (0.38) | TRPA1CASP3LMNAPOLBMAPT | |
| SCHEMBL24153255 | 0.86 | TRPA1 (0.40) | TRPA1CASP3LMNAPOLBMAPT | |
| SCHEMBL24152461 | 0.86 | TRPA1 (0.40) | TRPA1MAOAMAOBCASP3LMNA | |
| SCHEMBL24152465 | 0.85 | TRPA1 (0.40) | TRPA1CASP3LMNAPOLBMAPT | |
| SCHEMBL24151584 | 0.84 | TRPA1 (0.42) | TRPA1CASP3LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |