Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 9/20 | 0.38 |
| ▸ | CASP7 | P55210 | 9/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153249 | 0.91 | TRPA1 (0.41) | TRPA1CA1CA2CA9CA12 | |
| SCHEMBL24152362 | 0.87 | TRPA1 (0.53) | TRPA1CA1CA2CA9CA12 | |
| SCHEMBL24152359 | 0.86 | TRPA1 (0.50) | TRPA1CA1CA2CA9CA12 | |
| SCHEMBL24151575 | 0.84 | TRPA1 (0.61) | TRPA1CA1CA2CA9CA12 | |
| SCHEMBL24151764 | 0.83 | TRPA1 (0.49) | TRPA1CA1CA2CA9CA12 | |
| SCHEMBL24152517 | 0.82 | TRPA1 (0.48) | TRPA1 | |
| SCHEMBL24153267 | 0.81 | TRPA1 (0.48) | TRPA1CA1CA2CA9CA12 | |
| SCHEMBL24152847 | 0.81 | TRPA1 (0.41) | TRPA1CASP3CASP7 | |
| SCHEMBL24152372 | 0.81 | TRPA1 (0.47) | TRPA1CA2CA9CA12CASP3 | |
| SCHEMBL24151587 | 0.80 | TRPA1 (0.42) | TRPA1CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |