Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 7/20 | 0.42 |
| ▸ | FYN | P06241 | 4/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155867 | 0.87 | EGFR (0.41) | MEN1KMT2AHPGDSEGFRBTK | |
| SCHEMBL21995639 | 0.82 | MEN1 (0.52) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL24156328 | 0.82 | ALOX5AP (0.35) | MEN1NPC1RAB9AKMT2ATGFBR1 | |
| SCHEMBL1542371 | 0.81 | CHEK1 (0.49) | NPC1RAB9AKMT2ASMN1; SMN2FYN | |
| SCHEMBL24155451 | 0.77 | MEN1 (0.49) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL22044431 | 0.77 | KDR (0.55) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL24155657 | 0.75 | DYRK1A (0.55) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL24155656 | 0.74 | CDK8 (0.63) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL24155858 | 0.72 | DYRK1A (0.46) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL21644144 | 0.71 | DYRK1A (0.59) | MEN1KMT2AFYNTGFBR1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, SCN1B | MEN1 450/4885NPC1 1298/4885GAA 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.