Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414340 | 0.93 | LPAR1 (0.55) | LPAR1LPAR5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL2411428 | 0.90 | LPAR1 (0.49) | LPAR1LPAR5ALDH1A1TSHRKMT2A | |
| SCHEMBL2414586 | 0.88 | LPAR1 (0.55) | LPAR1LPAR5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL2415567 | 0.87 | MEN1 (0.43) | LPAR1LPAR5KDM4EALDH1A1HTT | |
| SCHEMBL2414646 | 0.79 | LPAR1 (0.46) | LPAR1LPAR5KDM4EALDH1A1TSHR | |
| SCHEMBL2414338 | 0.79 | LPAR1 (0.64) | LPAR1LPAR5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL2410449 | 0.77 | RAB9A (0.49) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2411426 | 0.77 | LPAR1 (0.56) | LPAR1LPAR5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL2414650 | 0.76 | HDAC1 (0.46) | LPAR1LPAR5ALDH1A1TSHRMEN1 | |
| SCHEMBL14015155 | 0.76 | LPAR1 (0.57) | LPAR1LPAR5KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |