Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24156425 | 0.82 | EGFR (0.51) | EGFRNPC1RAB9AKMT2AMAP2K7 | |
| SCHEMBL24156389 | 0.80 | PDE2A (0.41) | EGFRNPC1RAB9AKMT2ACLK4 | |
| SCHEMBL24156732 | 0.74 | EGFR (0.38) | EGFRIGF1RMAPTGAACDK1 | |
| SCHEMBL16201834 | 0.73 | NPC1 (0.51) | EGFRNPC1RAB9AKMT2ACLK4 | |
| SCHEMBL20489451 | 0.72 | KMT2A (0.52) | EGFRNPC1RAB9AKMT2ACLK4 | |
| SCHEMBL20489657 | 0.69 | NPC1 (0.50) | EGFRNPC1RAB9AKMT2ACLK4 | |
| SCHEMBL15059077 | 0.69 | RAB9A (0.51) | EGFRNPC1RAB9AKMT2AMAP2K7 | |
| SCHEMBL2994863 | 0.68 | EGFR (1.00) | EGFRKMT2AMEN1 | |
| SCHEMBL20489500 | 0.66 | MAPT (0.57) | EGFRNPC1RAB9AKMT2ACLK4 | |
| SCHEMBL1083657 | 0.66 | NPC1 (0.62) | EGFRNPC1RAB9AKMT2ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021259208-A1 | TYK-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-12-30 | — | — | WO | disclosed |