Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GAK | O14976 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24156731 | 0.74 | TNNI3K (0.46) | CDK1PTGS1PTGS2 | |
| SCHEMBL24156426 | 0.74 | EGFR (0.52) | EGFRIGF1RCDK1GAAMAPT | |
| SCHEMBL10036952 | 0.65 | DHODH (0.35) | EGFRIGF1RCDK1GAK | |
| SCHEMBL26598725 | 0.65 | LRRK2 (0.34) | IGF1RKAT2BBRD9 | |
| SCHEMBL6848815 | 0.65 | TSHR (0.41) | BRD4 | |
| SCHEMBL6847221 | 0.65 | TSHR (0.41) | BRD4 | |
| SCHEMBL4414965 | 0.65 | HSD17B14 (0.39) | MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6846381 | 0.64 | TSHR (0.39) | BRD4 | |
| Hydrochloric Acid SCHEMBL6841993 | 0.64 | TSHR (0.39) | BRD4 | |
| SCHEMBL21597191 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021259208-A1 | TYK-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-12-30 | — | — | WO | disclosed |