Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249327 | 0.79 | HTT (0.31) | CTSS | |
| SCHEMBL22810865 | 0.76 | HMGCR (0.31) | CTSS | |
| SCHEMBL10129385 | 0.75 | GABRA2 (0.37) | — | |
| SCHEMBL20282388 | 0.73 | IRAK4 (0.34) | CTSS | |
| SCHEMBL14417165 | 0.72 | AR (0.42) | CTSS | |
| SCHEMBL20997233 | 0.72 | — | — | |
| SCHEMBL22021705 | 0.72 | — | — | |
| SCHEMBL15059775 | 0.72 | — | — | |
| SCHEMBL25009052 | 0.72 | ACHE (0.35) | — | |
| SCHEMBL18812115 | 0.70 | DPP4 (0.32) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544975-B1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND USE | DANA FARBER CANCER INST INC (US) | 2022-01-05 | — | — | EP | disclosed |