Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174776 | 0.85 | GABRA1 (0.35) | DGAT1 | |
| SCHEMBL23573544 | 0.82 | TNF (0.32) | — | |
| SCHEMBL23573541 | 0.82 | TNF (0.32) | — | |
| SCHEMBL22482082 | 0.80 | ATM (0.37) | — | |
| SCHEMBL22482090 | 0.80 | ATM (0.37) | — | |
| SCHEMBL24334237 | 0.76 | GAA (0.32) | — | |
| SCHEMBL23148736 | 0.74 | RECQL (0.32) | — | |
| SCHEMBL14533783 | 0.74 | ALDH1A1 (0.34) | — | |
| SCHEMBL19919921 | 0.72 | PDK2 (0.32) | DGAT1 | |
| SCHEMBL26097178 | 0.70 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793565-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |