Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414109 | 0.92 | STING1 (0.36) | SLC2A1 | |
| SCHEMBL2413551 | 0.84 | TUBB4A (0.33) | PPARAMAPT | |
| SCHEMBL2414212 | 0.83 | THRA (0.32) | — | |
| SCHEMBL2418353 | 0.82 | — | — | |
| SCHEMBL2411784 | 0.71 | KCNH2 (0.38) | PPARAMAPT | |
| SCHEMBL2408631 | 0.70 | PPARD (0.46) | PPARAMAPT | |
| SCHEMBL2410358 | 0.69 | PPARA (0.41) | PPARAMAPTTP53 | |
| SCHEMBL2412706 | 0.68 | SLC22A12 (0.41) | PPARAMAPTTP53 | |
| SCHEMBL2414345 | 0.67 | PPARA (0.45) | PPARA | |
| SCHEMBL2418774 | 0.67 | PPARG (0.49) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | claimed |