Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.54 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.53 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.47 |
| ▸ | WIZ | O95785 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29632989 | 0.93 | CRBN (0.54) | CRBNIKZF2IKZF1 | |
| SCHEMBL24419601 | 0.93 | CRBN (0.54) | CRBNIKZF2IKZF1 | |
| SCHEMBL29632980 | 0.92 | CRBN (0.50) | CRBNIKZF2IKZF1 | |
| SCHEMBL24160339 | 0.92 | CRBN (0.50) | CRBNIKZF2IKZF1 | |
| SCHEMBL24160239 | 0.92 | CRBN (0.53) | CRBNIKZF2IKZF1 | |
| SCHEMBL24160826 | 0.91 | CRBN (0.52) | CRBNIKZF2IKZF1TNF | |
| SCHEMBL24160509 | 0.91 | CRBN (0.52) | CRBNIKZF2IKZF1TNF | |
| SCHEMBL24160287 | 0.91 | CRBN (0.52) | CRBNIKZF2IKZF1TNF | |
| SCHEMBL24160821 | 0.91 | CRBN (0.52) | CRBNIKZF2IKZF1TNF | |
| SCHEMBL29632990 | 0.91 | CRBN (0.52) | CRBNIKZF2IKZF1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606883-B | Sulfur-containing compound based on glutarimide skeleton and application thereof | 上海科技大学 | 2023-05-09 | — | — | CN | claimed |
| CN-111606883-A | Sulfur-containing compound based on glutarimide framework and application thereof | 上海科技大学 | 2020-09-01 | — | — | CN | claimed |
| US-12582641-B2 | Sulfur-containing compound based on glutarimide skeleton and application thereof | SHANGHAITECH UNIVERSITY (CN) | 2026-03-24 | — | — | US | disclosed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | disclosed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | disclosed |
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12582641-B2 | Sulfur-containing compound based on glutarimide skeleton and application thereof | SUCNR1, SRD5A1, GLS | CRBN 1235/4885IKZF2 4582/4885IKZF1 4354/4885 |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | GLS, SQOR, GCDH | CRBN 2779/4885IKZF2 3862/4885IKZF1 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.