Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.62 |
| ▸ | IKZF3 | Q9UKT9 | 12/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.43 |
| ▸ | NPM1 | P06748 | 1/20 | 0.43 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29632906 | 1.00 | CRBN (0.62) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL29632964 | 0.87 | CRBN (0.76) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL24160543 | 0.87 | CRBN (0.76) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL24419599 | 0.86 | CRBN (0.52) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL21493128 | 0.86 | CRBN (0.63) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL29632949 | 0.86 | CRBN (0.52) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL22549877 | 0.81 | CRBN (0.61) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL22532660 | 0.81 | CRBN (0.61) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL22549876 | 0.81 | CRBN (0.61) | CRBNDDB1IKZF3ADRA1DADRA1A | |
| SCHEMBL29532184 | 0.81 | CRBN (0.61) | CRBNDDB1IKZF3ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606883-B | Sulfur-containing compound based on glutarimide skeleton and application thereof | 上海科技大学 | 2023-05-09 | — | — | CN | claimed |
| CN-111606883-A | Sulfur-containing compound based on glutarimide framework and application thereof | 上海科技大学 | 2020-09-01 | — | — | CN | claimed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | disclosed |
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | disclosed |
| CN-111606883-A | Sulfur-containing compound based on glutarimide framework and application thereof | 上海科技大学 | 2020-09-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | GLS, SQOR, GCDH | CRBN 2779/4885DDB1 2606/4885IKZF3 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.