Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067906 | 0.79 | CACNA2D1 (0.53) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL18100237 | 0.76 | CACNA2D1 (0.42) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL466234 | 0.76 | CACNA2D1 (0.70) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL20381085 | 0.76 | CACNA2D1 (0.70) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL5917733 | 0.76 | CACNA2D1 (0.70) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL4198744 | 0.74 | MCL1 (0.33) | GABRR1DPP7MCL1RRM1FAAH | |
| SCHEMBL1755576 | 0.72 | — | — | |
| SCHEMBL14571059 | 0.71 | MCL1 (0.43) | MCL1FAAHALDH1A1 | |
| SCHEMBL12521583 | 0.71 | PSMB5 (0.38) | PSMB5CAPN1MCL1MMEFAAH | |
| SCHEMBL4010378 | 0.70 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067700-B1 | IMMUNOASSAY FOR PREGABALIN | RANDOX LABORATORIES LTD (GB) | 2022-01-05 | — | — | EP | disclosed |