Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25679894 | 0.92 | ADK (0.43) | ADKP2RX3LMNAHBBPMP22 | |
| SCHEMBL22883235 | 0.91 | ADK (0.40) | ADKMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24166706 | 0.90 | ADK (0.54) | ADKPAX8GMNNALDH1A1LMNA | |
| SCHEMBL23989399 | 0.90 | ADK (0.54) | ADKPAX8GMNNALDH1A1LMNA | |
| SCHEMBL21137753 | 0.90 | ADK (0.54) | ADKPAX8GMNNALDH1A1LMNA | |
| SCHEMBL22990432 | 0.90 | ADK (0.54) | ADKPAX8GMNNALDH1A1LMNA | |
| SCHEMBL23211481 | 0.90 | ADK (0.54) | ADKPAX8GMNNALDH1A1LMNA | |
| SCHEMBL18510882 | 0.90 | ADK (0.54) | ADKPAX8GMNNALDH1A1LMNA | |
| SCHEMBL22883157 | 0.87 | ADK (0.43) | ADKP2RX3MEN1KMT2AALDH1A1 | |
| SCHEMBL23989393 | 0.86 | ADK (0.46) | ADKPAX8MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707151-B1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICALS CO (JP) | 2022-01-05 | — | — | EP | disclosed |