Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 5/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23211481 | 1.00 | ADK (0.54) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL22990432 | 1.00 | ADK (0.54) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL21137753 | 1.00 | ADK (0.54) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL18510882 | 1.00 | ADK (0.54) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL23989399 | 1.00 | ADK (0.54) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL23989440 | 0.91 | ADK (0.46) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL23989393 | 0.91 | ADK (0.46) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL24166703 | 0.90 | ADK (0.45) | ADKPAX8ALDH1A1HTTRAB9A | |
| SCHEMBL25679899 | 0.90 | ADK (0.52) | ADKMAPTLMNAPMP22 | |
| SCHEMBL22883157 | 0.87 | ADK (0.43) | ADKALDH1A1HTTDOT1LTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707151-B1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICALS CO (JP) | 2022-01-05 | — | — | EP | disclosed |