SCHEMBL241668

SCHEMBL241668

FC(c1ccccc1)(c1ccccc1)C1CCNCC1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.61
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.61
CYP2D6 P10635 1/20 0.61
SCN1A P35498 1/20 0.61
KMT2A Q03164 1/20 0.61
SCN2A Q99250 1/20 0.61
SCN3A Q9NY46 1/20 0.61
HTR2C P28335 6/20 0.46
GBA1 P04062 1/20 0.46
SLC18A3 Q16572 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
DCUN1D1 Q96GG9 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21752562 0.82 HRH1 (0.59) HRH1MEN1LMNACYP2D6SCN1A
SCHEMBL7070401 0.76 HRH1 (0.61) HRH1MEN1LMNACYP2D6SCN1A
SCHEMBL29199169 0.76 HRH1 (0.61) HRH1MEN1LMNACYP2D6SCN1A
SCHEMBL11606097 0.76 HRH1 (0.61) HRH1MEN1LMNACYP2D6SCN1A
Azacyclonol SCHEMBL241817 0.76 HRH1 (1.00) HRH1MEN1LMNACYP2D6SCN1A
SCHEMBL5765286 0.76 GBA1 (0.50) HRH1MEN1LMNACYP2D6SCN1A
Hydrochloric Acid SCHEMBL19409608 0.74 HRH1 (0.59) HRH1MEN1LMNACYP2D6SCN1A
Azacyclonol SCHEMBL6135637 0.74 HRH1 (0.96) HRH1MEN1LMNACYP2D6SCN1A
Azacyclonol SCHEMBL1890138 0.74 HRH1 (0.96) HRH1MEN1LMNACYP2D6SCN1A
SCHEMBL3951181 0.74 CYP2D6 (0.70) HRH1MEN1LMNACYP2D6SCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
EP-3438106-A1 ANTI-VIRAL COMPOUNDS AbbVie Ireland Unlimited Company (IE) 2019-02-06 EP disclosed
EP-3438109-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2019-02-06 EP disclosed
EP-3438106-A1 ANTI-VIRAL COMPOUNDS AbbVie Ireland Unlimited Company (IE) 2019-02-06 EP disclosed
US-20190015402-A1 Anti-Viral Compounds ABBVIE INC. (US) 2019-01-17 US disclosed
US-20190015402-A1 Anti-Viral Compounds ABBVIE INC. (US) 2019-01-17 US disclosed
US-10039754-B2 Anti-viral compounds ABBVIE INC. (US) 2018-08-07 US disclosed
US-10039754-B2 Anti-viral compounds ABBVIE INC. (US) 2018-08-07 US disclosed
US-20120220562-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-08-30 US disclosed
US-20120220562-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-08-30 US disclosed
WO-2012051361-A1 ANTI-VIRAL COMPOUNDS ABBOTT LABORATORIES (US) 2012-04-19 WO disclosed
WO-2012051361-A1 ANTI-VIRAL COMPOUNDS ABBOTT LABORATORIES (US) 2012-04-19 WO disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS HRH1 3557/4885MEN1 4681/4885LMNA 3118/4885
US-20120220562-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS HRH1 3557/4885MEN1 4681/4885LMNA 3118/4885
US-20110207699-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS HRH1 3557/4885MEN1 4681/4885LMNA 3118/4885
US-20190015402-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS HRH1 3557/4885MEN1 4681/4885LMNA 3118/4885
US-20120004196-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS HRH1 3557/4885MEN1 4681/4885LMNA 3118/4885
US-10039754-B2 Anti-viral compounds HAVCR2, EIF2AK2, MAVS HRH1 3557/4885MEN1 4681/4885LMNA 3118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.